Catalytic Z-selective cross-metathesis with secondary silyl- and benzyl-protected allylic ethers: mechanistic aspects and applications to natural product synthesis.
نویسندگان
چکیده
Citation Mann, Tyler J., Alexander W. H. Speed, Richard R. Schrock, and Amir H. Hoveyda. “Catalytic Z-Selective Cross-Metathesis with Secondary Silyland Benzyl-Protected Allylic Ethers: Mechanistic Aspects and Applications to Natural Product Synthesis.” Angewandte Chemie International Edition 52, no. 32 (August 5, 2013): 8395-8400. As Published http://dx.doi.org/10.1002/anie.201302538 Publisher Wiley Blackwell
منابع مشابه
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The Z-selective cross metathesis of allylic-substituted olefins is explored with recently developed ruthenium-based metathesis catalysts. The reaction proceeds with excellent stereoselectivity for the Zisomer (typically >95%) and yields of up to 88% for a variety of allylic substituents. This includes the first synthesis of Z-a,b-unsaturated acetals by cross metathesis and their elaboration to ...
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ورودعنوان ژورنال:
- Angewandte Chemie
دوره 52 32 شماره
صفحات -
تاریخ انتشار 2013